NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. [electronic resource]
Producer: 20100615Description: 1357-61 p. digitalISSN:- 1476-4687
- Animals
- Apoptosis Regulatory Proteins
- Atherosclerosis -- chemically induced
- Bone Marrow Transplantation
- CARD Signaling Adaptor Proteins
- Carrier Proteins -- genetics
- Cathepsin B -- metabolism
- Cathepsin L -- metabolism
- Cholesterol -- chemistry
- Crystallization
- Cytoskeletal Proteins -- deficiency
- Diet, Atherogenic
- Female
- Humans
- Inflammation -- chemically induced
- Interleukin-1 -- deficiency
- Interleukin-18 -- metabolism
- Lysosomes -- drug effects
- Mice
- Mice, Inbred C57BL
- NLR Family, Pyrin Domain-Containing 3 Protein
- Peritoneal Cavity -- pathology
- Phagocytes -- drug effects
- Receptors, LDL -- deficiency
- Time Factors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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