The tyrosine 343 residue of nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) is important for its interaction with SHP1, a cytoplasmic tyrosine phosphatase with tumor suppressor functions. [electronic resource]
Producer: 20100824Description: 19813-20 p. digitalISSN:- 1083-351X
- Anaplastic Lymphoma Kinase
- Binding Sites -- genetics
- Blotting, Western
- Cell Line
- Cell Line, Tumor
- Humans
- Immunoprecipitation
- Mutation
- Nuclear Proteins -- genetics
- Nucleophosmin
- Oncogene Proteins, Fusion -- genetics
- Phosphorylation
- Protein Binding
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 -- genetics
- Protein-Tyrosine Kinases -- genetics
- Receptor Protein-Tyrosine Kinases
- Transfection
- Tumor Stem Cell Assay
- Tumor Suppressor Proteins -- genetics
- Tyrosine -- genetics
- src Homology Domains -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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