In vitro to in vivo comparison of the substrate characteristics of sorafenib tosylate toward P-glycoprotein. [electronic resource]
Producer: 20101130Description: 1341-6 p. digitalISSN:- 1521-009X
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- metabolism
- Animals
- Anti-Arrhythmia Agents -- metabolism
- Benzenesulfonates -- blood
- Brain -- metabolism
- Caco-2 Cells
- Digoxin -- metabolism
- Humans
- LLC-PK1 Cells
- Male
- Mice
- Mice, Knockout
- Niacinamide -- analogs & derivatives
- Permeability
- Phenylurea Compounds
- Protein Kinase Inhibitors -- blood
- Pyridines -- blood
- Sorafenib
- Swine
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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