Structure-activity relationships of bioisosteric replacement of the carboxylic acid in novel androgen receptor pure antagonists. [electronic resource]
Producer: 20100910Description: 3159-68 p. digitalISSN:- 1464-3391
- Androgen Antagonists -- chemical synthesis
- Animals
- Antineoplastic Agents, Hormonal -- chemical synthesis
- Carboxylic Acids -- chemical synthesis
- Cell Line, Tumor
- Dose-Response Relationship, Drug
- Inhibitory Concentration 50
- Male
- Mice
- Mice, SCID
- Molecular Structure
- Nitriles -- chemical synthesis
- Prostatic Neoplasms -- drug therapy
- Sulfonamides -- chemical synthesis
- Thiohydantoins -- chemical synthesis
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article
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