Lovastatin induces VSMC differentiation through inhibition of Rheb and mTOR. [electronic resource]
Producer: 20100713Description: C119-27 p. digitalISSN:- 1522-1563
- Angioplasty, Balloon
- Animals
- Cardiovascular Agents -- pharmacology
- Cell Differentiation -- drug effects
- Cells, Cultured
- Contractile Proteins -- metabolism
- Dose-Response Relationship, Drug
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Intracellular Signaling Peptides and Proteins -- antagonists & inhibitors
- Lovastatin -- pharmacology
- Mechanistic Target of Rapamycin Complex 1
- Monomeric GTP-Binding Proteins -- antagonists & inhibitors
- Multiprotein Complexes
- Muscle, Smooth, Vascular -- drug effects
- Myocytes, Smooth Muscle -- drug effects
- Neuropeptides -- antagonists & inhibitors
- Phosphorylation
- Protein Kinase Inhibitors -- pharmacology
- Protein Prenylation
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Proteins
- RNA Interference
- Ras Homolog Enriched in Brain Protein
- Signal Transduction -- drug effects
- Swine
- TOR Serine-Threonine Kinases
- Time Factors
- Tissue Culture Techniques
- Transcription Factors -- metabolism
- Transfection
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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