Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes. [electronic resource]
Producer: 20100827Description: 1395-405 p. digitalISSN:- 1432-0428
- Aged
- Cell Line
- Chemokine CCL2 -- metabolism
- Chemokine CXCL1
- Diabetes Mellitus, Type 2 -- metabolism
- Enzyme-Linked Immunosorbent Assay
- Female
- Fluorescent Antibody Technique
- Humans
- In Vitro Techniques
- Insulin-Secreting Cells -- metabolism
- Interleukin-6 -- metabolism
- Interleukin-8 -- metabolism
- Islets of Langerhans -- drug effects
- Male
- Middle Aged
- NF-kappa B -- metabolism
- Oligonucleotide Array Sequence Analysis
- Palmitates -- pharmacology
- Polymerase Chain Reaction
- Radioimmunoassay
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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