Intrathecal injection of an alpha seven nicotinic acetylcholine receptor agonist attenuates gp120-induced mechanical allodynia and spinal pro-inflammatory cytokine profiles in rats. [electronic resource]
Producer: 20101008Description: 959-67 p. digitalISSN:- 1090-2139
- Animals
- Benzylidene Compounds -- pharmacology
- Cytokines -- biosynthesis
- DNA Primers
- DNA, Complementary -- biosynthesis
- HIV Envelope Protein gp120 -- antagonists & inhibitors
- Injections, Spinal
- Interleukin-1beta -- biosynthesis
- Male
- Nerve Tissue Proteins -- biosynthesis
- Nicotinic Agonists -- administration & dosage
- Pain -- chemically induced
- Physical Stimulation
- Pyridines -- pharmacology
- RNA, Messenger -- biosynthesis
- Rats
- Rats, Sprague-Dawley
- Receptors, Nicotinic -- drug effects
- Reverse Transcriptase Polymerase Chain Reaction
- Spinal Cord -- drug effects
- Tumor Necrosis Factor-alpha -- biosynthesis
- alpha7 Nicotinic Acetylcholine Receptor
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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