Cardiac cell therapy with mesenchymal stem cell induces cardiac nerve sprouting, angiogenesis, and reduced connexin43-positive gap junctions, but concomitant electrical pacing increases connexin43-positive gap junctions in canine heart. [electronic resource]
Producer: 20100928Description: 308-17 p. digitalISSN:- 1467-1107
- Animals
- Arrhythmias, Cardiac -- metabolism
- Cardiac Pacing, Artificial -- methods
- Cells, Cultured
- Connexin 43 -- biosynthesis
- Disease Models, Animal
- Dogs
- Gap Junctions -- genetics
- Gene Expression Regulation
- Heart -- innervation
- Heart Rate
- Humans
- Immunohistochemistry
- Mesenchymal Stem Cell Transplantation -- methods
- Neovascularization, Physiologic
- Polymerase Chain Reaction
- RNA, Messenger -- biosynthesis
- Sympathetic Nervous System -- metabolism
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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