Amphotericin B, identified from a natural product screen, antagonizes CNS inhibitors to promote axon growth via activation of an Akt pathway in neurons. [electronic resource]
Producer: 20100708Description: 1331-42 p. digitalISSN:- 1471-4159
- Amphotericin B -- pharmacology
- Animals
- Antifungal Agents -- pharmacology
- Axons -- drug effects
- Biological Products -- pharmacology
- Blotting, Western
- Cell Proliferation -- drug effects
- Chondroitin Sulfate Proteoglycans -- antagonists & inhibitors
- Drug Evaluation, Preclinical
- Myelin-Associated Glycoprotein -- antagonists & inhibitors
- Nerve Regeneration -- drug effects
- Neurites -- drug effects
- Neurons -- drug effects
- Oncogene Protein v-akt -- metabolism
- Principal Component Analysis
- Rats
- Signal Transduction -- drug effects
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Publication Type: Journal Article
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