Aldose reductase regulates vascular smooth muscle cell proliferation by modulating G1/S phase transition of cell cycle. [electronic resource]
Producer: 20100608Description: 2140-50 p. digitalISSN:- 1945-7170
- Aldehyde Reductase -- antagonists & inhibitors
- Animals
- Aorta -- metabolism
- Blotting, Western
- Cell Cycle -- drug effects
- Cell Proliferation
- Cell Survival -- drug effects
- Cells, Cultured
- Cyclins -- genetics
- Diabetes Mellitus, Experimental -- genetics
- Dose-Response Relationship, Drug
- E2F1 Transcription Factor -- genetics
- G1 Phase
- Glucose -- pharmacology
- Imidazolidines -- pharmacology
- Male
- Muscle, Smooth, Vascular -- cytology
- Phosphorylation -- drug effects
- RNA Interference
- Rats
- Rats, Sprague-Dawley
- Retinoblastoma Protein -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- S Phase
- Tumor Necrosis Factor-alpha -- pharmacology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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