Randomized, double-blind, placebo-controlled, single intravenous dose-escalation study to evaluate the safety, tolerability, and pharmacokinetics of the novel coronary smooth muscle cell proliferation inhibitor Biolimus A9 in healthy individuals. [electronic resource]
Producer: 20110323Description: 29-39 p. digitalISSN:- 1552-4604
- Adult
- Cell Proliferation -- drug effects
- Chromatography, Liquid
- Dose-Response Relationship, Drug
- Double-Blind Method
- Female
- Half-Life
- Humans
- Immunosuppressive Agents -- administration & dosage
- Infusions, Intravenous
- Male
- Middle Aged
- Myocytes, Smooth Muscle -- drug effects
- Sirolimus -- administration & dosage
- Tandem Mass Spectrometry
- Tissue Distribution
- Young Adult
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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