Synthesis and preliminary pharmacological characterisation of a new class of nitrogen-containing bisphosphonates (N-BPs). [electronic resource]
Producer: 20100702Description: 2428-38 p. digitalISSN:- 1464-3391
- Animals
- Aorta, Thoracic -- drug effects
- Bone Density Conservation Agents -- chemical synthesis
- Bone and Bones -- drug effects
- Cells, Cultured
- Chromatography, Affinity
- Diphosphonates -- chemical synthesis
- Durapatite -- chemistry
- Farnesyl-Diphosphate Farnesyltransferase -- antagonists & inhibitors
- Humans
- Ibandronic Acid
- In Vitro Techniques
- Macrophages -- drug effects
- Magnetic Resonance Spectroscopy
- Male
- Mice
- Microsomes, Liver -- drug effects
- Models, Molecular
- Muscle, Smooth, Vascular -- drug effects
- Nitric Oxide Donors -- chemical synthesis
- Nitrogen -- chemistry
- Osteogenesis -- drug effects
- Rats
- Rats, Wistar
- Vasodilator Agents -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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