Catecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor. [electronic resource]
Producer: 20100524Description: 1413-24 p. digitalISSN:- 1524-4571
- Animals
- Caffeine
- Calcium Signaling -- genetics
- Cells, Cultured
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Disease Models, Animal
- Epinephrine
- Excitation Contraction Coupling
- Genotype
- Isoproterenol
- Membrane Potentials
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Myocardial Contraction
- Myocytes, Cardiac -- metabolism
- Peptide Fragments -- metabolism
- Phenotype
- Phosphorylation
- Physical Exertion
- Point Mutation
- Protein Conformation
- Protein Structure, Tertiary
- Ryanodine Receptor Calcium Release Channel -- chemistry
- Sarcoplasmic Reticulum -- metabolism
- Structure-Activity Relationship
- Tachycardia, Ventricular -- chemically induced
- Time Factors
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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