Inhibition of JAK/STAT signaling pathway prevents high-glucose-induced increase in endothelin-1 synthesis in human endothelial cells. [electronic resource]
Producer: 20100615Description: 71-9 p. digitalISSN:- 1432-0878
- Cells, Cultured
- Diabetic Angiopathies -- genetics
- Endothelial Cells -- cytology
- Endothelin-1 -- biosynthesis
- Enzyme Inhibitors -- pharmacology
- Glucose -- metabolism
- Humans
- Hyperglycemia -- metabolism
- Janus Kinases -- antagonists & inhibitors
- Promoter Regions, Genetic -- drug effects
- RNA, Messenger -- drug effects
- STAT Transcription Factors -- antagonists & inhibitors
- STAT1 Transcription Factor -- antagonists & inhibitors
- Signal Transduction -- drug effects
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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