Akt inhibition up-regulates MMP1 through a CCN2-dependent pathway in human dermal fibroblasts. [electronic resource]
Producer: 20101115Description: 347-54 p. digitalISSN:- 1600-0625
- Butadienes -- pharmacology
- Cells, Cultured
- Collagen Type I -- metabolism
- Connective Tissue Growth Factor -- genetics
- Fibroblasts -- drug effects
- Gene Expression -- drug effects
- Humans
- Matrix Metalloproteinase 1 -- metabolism
- Mitogen-Activated Protein Kinase 3 -- antagonists & inhibitors
- Nitriles -- pharmacology
- Phosphorylation -- genetics
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Protein c-ets-1 -- metabolism
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Proto-Oncogene Proteins c-jun -- metabolism
- RNA, Small Interfering -- genetics
- Signal Transduction -- drug effects
- Skin -- cytology
- Transduction, Genetic
- Transforming Growth Factor beta -- pharmacology
- Up-Regulation -- drug effects
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Publication Type: Journal Article
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