Interleukin-34 is expressed by giant cell tumours of bone and plays a key role in RANKL-induced osteoclastogenesis. [electronic resource]
Producer: 20100511Description: 77-86 p. digitalISSN:- 1096-9896
- Adult
- Aged
- Animals
- Anisoles -- pharmacology
- Bone Neoplasms -- metabolism
- Bone Resorption -- metabolism
- CD11b Antigen -- analysis
- Carcinoma, Giant Cell -- metabolism
- Cell Adhesion -- drug effects
- Cell Proliferation -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Dose-Response Relationship, Drug
- Female
- Humans
- Interleukins -- biosynthesis
- Male
- Mice
- Mice, Inbred C57BL
- Middle Aged
- Neoplasm Proteins -- biosynthesis
- Osteoclasts -- cytology
- Pyrimidines -- pharmacology
- RANK Ligand -- pharmacology
- Receptor, Macrophage Colony-Stimulating Factor -- antagonists & inhibitors
- Signal Transduction -- physiology
- Young Adult
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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