Genetic modulation of the Let-7 microRNA binding to KRAS 3'-untranslated region and survival of metastatic colorectal cancer patients treated with salvage cetuximab-irinotecan. [electronic resource]
Producer: 20110225Description: 458-64 p. digitalISSN:- 1473-1150
- 3' Untranslated Regions
- Adult
- Aged
- Antibodies, Monoclonal -- administration & dosage
- Antibodies, Monoclonal, Humanized
- Antineoplastic Combined Chemotherapy Protocols -- administration & dosage
- Camptothecin -- administration & dosage
- Cetuximab
- Cohort Studies
- Colorectal Neoplasms -- drug therapy
- Disease-Free Survival
- Female
- Genotype
- Humans
- Irinotecan
- Male
- MicroRNAs -- genetics
- Middle Aged
- Neoplasm Metastasis
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins p21(ras)
- Retrospective Studies
- Salvage Therapy
- ras Proteins -- genetics
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Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
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