Curcumin inhibits TNFalpha-induced lectin-like oxidised LDL receptor-1 (LOX-1) expression and suppresses the inflammatory response in human umbilical vein endothelial cells (HUVECs) by an antioxidant mechanism. [electronic resource]
Producer: 20110104Description: 720-9 p. digitalISSN:- 1475-6374
- Anti-Inflammatory Agents, Non-Steroidal -- adverse effects
- Antioxidants -- adverse effects
- Cell Adhesion Molecules -- metabolism
- Cell Survival -- drug effects
- Cells, Cultured
- Chemokine CCL2 -- metabolism
- Curcuma -- chemistry
- Curcumin -- adverse effects
- Endothelium, Vascular -- drug effects
- Humans
- I-kappa B Proteins -- metabolism
- Lipid Peroxidation -- drug effects
- NF-KappaB Inhibitor alpha
- NF-kappa B -- metabolism
- Nitric Oxide Synthase Type III -- metabolism
- Oxidative Stress -- drug effects
- Phosphorylation -- drug effects
- Plant Extracts -- chemistry
- Protein Transport -- drug effects
- Reactive Nitrogen Species -- chemistry
- Reactive Oxygen Species -- chemistry
- Scavenger Receptors, Class E -- metabolism
- Tumor Necrosis Factor-alpha -- antagonists & inhibitors
- Umbilical Veins -- cytology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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