Reduction of the ring size of radiolabeled lactam bridge-cyclized alpha-MSH peptide, resulting in enhanced melanoma uptake. [electronic resource]
Producer: 20100402Description: 418-26 p. digitalISSN:- 1535-5667
- Amino Acid Sequence
- Animals
- Biological Transport
- Cell Line, Tumor
- Chelating Agents -- chemistry
- Cyclization
- Female
- Heterocyclic Compounds, 1-Ring -- chemistry
- Indium Radioisotopes -- chemistry
- Lactams -- chemistry
- Melanoma -- diagnostic imaging
- Mice
- Receptor, Melanocortin, Type 1 -- metabolism
- Structure-Activity Relationship
- Tissue Distribution
- Tomography, Emission-Computed, Single-Photon
- Tomography, X-Ray Computed
- alpha-MSH -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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