Protein tyrosine phosphatase SHP-1 positively regulates TLR-induced IL-12p40 production in macrophages through inhibition of phosphatidylinositol 3-kinase. [electronic resource]
Producer: 20100520Description: 845-55 p. digitalISSN:- 1938-3673
- Animals
- Cell Separation
- Enzyme-Linked Immunosorbent Assay
- Flow Cytometry
- Immunoprecipitation
- Interleukin-12 Subunit p40 -- biosynthesis
- Macrophages -- immunology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Phosphatidylinositol 3-Kinases -- immunology
- Protein Tyrosine Phosphatase, Non-Receptor Type 6 -- immunology
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- immunology
- Toll-Like Receptors -- immunology
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Publication Type: Journal Article
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