Enhancement of effector CD8+ T-cell function by tumour-associated B7-H3 and modulation of its counter-receptor triggering receptor expressed on myeloid cell-like transcript 2 at tumour sites. [electronic resource]
Producer: 20100826Description: 363-73 p. digitalISSN:- 1365-2567
- Animals
- Antibodies, Monoclonal -- immunology
- Antigens, CD -- metabolism
- Antigens, Differentiation, T-Lymphocyte -- metabolism
- B7 Antigens
- B7-1 Antigen -- genetics
- CD4-Positive T-Lymphocytes -- immunology
- CD8-Positive T-Lymphocytes -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cytokines -- pharmacology
- Cytotoxicity, Immunologic -- immunology
- Female
- Interferon-gamma -- metabolism
- Lectins, C-Type -- metabolism
- Lymph Nodes -- cytology
- Lymphocyte Activation -- immunology
- Lymphocyte Depletion
- Melanoma, Experimental -- immunology
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mice, Nude
- Mice, Transgenic
- Neoplasms -- immunology
- Ovalbumin -- genetics
- Receptors, Immunologic -- genetics
- T-Lymphocytes, Cytotoxic -- immunology
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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