An Achilles' heel in an amyloidogenic protein and its repair: insulin fibrillation and therapeutic design. [electronic resource]
Producer: 20100514Description: 10806-21 p. digitalISSN:- 1083-351X
- Amyloid -- chemistry
- Animals
- Antibiotics, Antineoplastic -- toxicity
- Crystallography, X-Ray
- Diabetes Mellitus, Experimental -- chemically induced
- Drug Design
- Humans
- Insulin -- chemistry
- Magnetic Resonance Spectroscopy
- Male
- Protein Structure, Secondary
- Rats
- Rats, Inbred Lew
- Receptor, IGF Type 1 -- metabolism
- Streptozocin -- toxicity
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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