Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells. [electronic resource]
Producer: 20100507Description: 1920-30 p. digitalISSN:- 1528-0012
- Adenovirus E1A Proteins -- metabolism
- Animals
- Carbon Tetrachloride
- Carcinoma, Hepatocellular -- genetics
- Cell Cycle -- drug effects
- Cell Proliferation -- drug effects
- Chemical and Drug Induced Liver Injury -- genetics
- Cyclin-Dependent Kinase 4 -- antagonists & inhibitors
- Cyclin-Dependent Kinase 6 -- antagonists & inhibitors
- Cyclin-Dependent Kinase Inhibitor p16 -- metabolism
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Disease Models, Animal
- E2F Transcription Factors -- metabolism
- Gene Knockdown Techniques
- Hep G2 Cells
- Hepatocytes -- drug effects
- Humans
- Liver Neoplasms -- genetics
- Male
- Mice
- Mice, Knockout
- Mice, Nude
- Neoplasm Transplantation
- Phosphorylation
- Piperazines -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Purines -- pharmacology
- Pyridines -- pharmacology
- RNA Interference
- Retinoblastoma Protein -- deficiency
- Retinoblastoma-Like Protein p107 -- metabolism
- Roscovitine
- Time Factors
- Transfection
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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