A novel inhibitor of plasminogen activator inhibitor-1 provides antithrombotic benefits devoid of bleeding effect in nonhuman primates. [electronic resource]
Producer: 20100527Description: 904-12 p. digitalISSN:- 1559-7016
- 4-Aminobenzoic Acid -- chemical synthesis
- Animals
- Disease Models, Animal
- Drug Design
- Female
- Fibrinolytic Agents -- chemical synthesis
- Hemorrhage -- drug therapy
- Humans
- Macaca fascicularis
- Male
- Mice
- Models, Molecular
- Molecular Structure
- Piperazines -- chemical synthesis
- Plasminogen Activator Inhibitor 1 -- chemistry
- Protein Conformation
- Rats
- Rats, Sprague-Dawley
- Rats, Wistar
- Serine Proteinase Inhibitors -- chemistry
- Structure-Activity Relationship
- Thrombosis -- drug therapy
- Ticlopidine -- pharmacology
- Tissue Plasminogen Activator -- therapeutic use
- para-Aminobenzoates
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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