WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-kappaB activation. [electronic resource]
Producer: 20100226Description: 815-20 p. digitalISSN:- 1091-6490
- Adaptor Proteins, Signal Transducing -- genetics
- Animals
- DNA Primers
- Histone-Lysine N-Methyltransferase -- immunology
- Humans
- Immunity, Innate
- Interferon Regulatory Factor-3 -- genetics
- Intracellular Signaling Peptides and Proteins
- Mice
- Molecular Biology -- methods
- NF-kappa B -- genetics
- Plasmids
- Proteins -- immunology
- RNA, Viral -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Toll-Like Receptors -- physiology
- Transcriptional Activation
- Virus Diseases -- genetics
- Viruses -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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