A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan. [electronic resource]
Producer: 20100412Description: 736-42 p. digitalISSN:- 1557-3265
- Adult
- Aged
- Algorithms
- Antineoplastic Agents, Phytogenic -- administration & dosage
- Camptothecin -- administration & dosage
- Carcinoma -- drug therapy
- Colorectal Neoplasms -- drug therapy
- Cytochrome P-450 CYP3A -- genetics
- Drug Dosage Calculations
- Female
- Humans
- Individuality
- Irinotecan
- Male
- Midazolam -- administration & dosage
- Middle Aged
- Models, Biological
- Neoplasm Metastasis
- Phenotype
- Precision Medicine -- methods
- Prodrugs -- administration & dosage
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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