The G12 family proteins upregulate matrix metalloproteinase-2 via p53 leading to human breast cell invasion. [electronic resource]
Producer: 20110131Description: 49-61 p. digitalISSN:- 1573-7217
- Adult
- Aged
- Aged, 80 and over
- Binding Sites
- Breast Neoplasms -- enzymology
- Carcinoma, Ductal, Breast -- enzymology
- Cell Line, Tumor
- Cell Movement
- Female
- GTP-Binding Protein alpha Subunits, G12-G13 -- genetics
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Neoplastic
- Genotype
- Humans
- MAP Kinase Kinase 3 -- metabolism
- MAP Kinase Kinase 6 -- metabolism
- Matrix Metalloproteinase 2 -- genetics
- Middle Aged
- Mutation
- Neoplasm Invasiveness
- Phenotype
- Promoter Regions, Genetic
- Proto-Oncogene Proteins c-akt -- metabolism
- Transcription, Genetic
- Transfection
- Tumor Suppressor Protein p53 -- metabolism
- Up-Regulation
- p38 Mitogen-Activated Protein Kinases -- metabolism
- rac1 GTP-Binding Protein -- metabolism
- ras Proteins -- metabolism
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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