Semisynthetic latrunculin derivatives as inhibitors of metastatic breast cancer: biological evaluations, preliminary structure-activity relationship and molecular modeling studies. [electronic resource]
Producer: 20100422Description: 274-85 p. digitalISSN:- 1860-7187
- Actins -- antagonists & inhibitors
- Animals
- Antineoplastic Agents -- chemical synthesis
- Binding Sites
- Breast Neoplasms -- drug therapy
- Bridged Bicyclo Compounds, Heterocyclic -- chemical synthesis
- Cell Line, Tumor
- Computer Simulation
- Crystallography, X-Ray
- Female
- Humans
- Hydrogen Bonding
- Models, Chemical
- Models, Molecular
- Neoplasm Metastasis
- Structure-Activity Relationship
- Thiazolidines -- chemical synthesis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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