Amino acid substitutions in an alpha-helical antimicrobial arachnid peptide affect its chemical properties and biological activity towards pathogenic bacteria but improves its therapeutic index. [electronic resource]
Producer: 20110420Description: 61-8 p. digitalISSN:- 1438-2199
- Amino Acid Sequence
- Amino Acid Substitution
- Animals
- Anti-Bacterial Agents -- chemical synthesis
- Gram-Positive Bacteria -- drug effects
- Humans
- Hydrophobic and Hydrophilic Interactions
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Peptides -- chemical synthesis
- Protein Structure, Secondary
- Scorpions -- chemistry
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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