Mycobacterial antigen(s) induce anergy by altering TCR- and TCR/CD28-induced signalling events: insights into T-cell unresponsiveness in leprosy. [electronic resource]
Producer: 20100223Description: 943-52 p. digitalISSN:- 1872-9142
- Antigens, Bacterial -- immunology
- Antigens, CD -- immunology
- Antigens, Differentiation, T-Lymphocyte -- immunology
- CD28 Antigens -- immunology
- Calcium -- immunology
- Cell Proliferation -- drug effects
- Clonal Anergy -- drug effects
- Enzyme Inhibitors -- pharmacology
- Gene Expression Regulation -- drug effects
- Humans
- Interleukin-2 -- immunology
- Interleukin-2 Receptor alpha Subunit -- immunology
- Ionomycin -- pharmacology
- Ionophores -- pharmacology
- Jurkat Cells
- Lectins, C-Type -- immunology
- Leprosy -- immunology
- Lymphocyte Activation -- drug effects
- MAP Kinase Signaling System -- drug effects
- Mitogen-Activated Protein Kinase 3 -- immunology
- Mycobacterium leprae -- immunology
- NFATC Transcription Factors -- immunology
- Promoter Regions, Genetic -- immunology
- Protein Kinase C -- immunology
- Receptors, Antigen, T-Cell -- immunology
- T-Lymphocytes -- immunology
- Thapsigargin -- pharmacology
- ZAP-70 Protein-Tyrosine Kinase -- immunology
- p38 Mitogen-Activated Protein Kinases -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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