ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage. [electronic resource]
Producer: 20100511Description: 4909-19 p. digitalISSN:- 1083-351X
- Apoptosis -- drug effects
- Ataxia Telangiectasia Mutated Proteins
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- Cell Nucleus -- metabolism
- Cysteine Proteinase Inhibitors -- toxicity
- DNA Damage -- genetics
- DNA-Binding Proteins -- genetics
- Doxorubicin -- toxicity
- Etoposide -- toxicity
- Humans
- Immunohistochemistry
- Immunoprecipitation
- In Situ Nick-End Labeling
- Leupeptins -- toxicity
- Phosphorylation -- drug effects
- Protein Binding -- drug effects
- Protein Serine-Threonine Kinases -- genetics
- Protein-Tyrosine Kinases -- genetics
- Proto-Oncogene Proteins c-mdm2 -- genetics
- Tumor Suppressor Protein p53 -- metabolism
- Tumor Suppressor Proteins -- genetics
- Ubiquitination -- genetics
- Dyrk Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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