The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: overall results and results in genotypic subgroups defined by mutations in NPM1, FLT3, and CEBPA. [electronic resource]
Producer: 20100305Description: 948-56 p. digitalISSN:- 1528-0020
- Adolescent
- Adult
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- CCAAT-Enhancer-Binding Proteins -- genetics
- Child
- Child, Preschool
- Cytarabine -- administration & dosage
- Daunorubicin -- administration & dosage
- Female
- Gene Expression Regulation, Leukemic
- Genotype
- Humans
- Infant
- Infant, Newborn
- Leukemia, Promyelocytic, Acute -- drug therapy
- Male
- Middle Aged
- Mutation
- Nuclear Proteins -- genetics
- Nucleophosmin
- Reverse Transcriptase Polymerase Chain Reaction
- Thioguanine -- administration & dosage
- Treatment Outcome
- Tretinoin -- administration & dosage
- Young Adult
- fms-Like Tyrosine Kinase 3 -- genetics
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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