Trafficking-deficient long QT syndrome mutation KCNQ1-T587M confers severe clinical phenotype by impairment of KCNH2 membrane localization: evidence for clinically significant IKr-IKs alpha-subunit interaction. [electronic resource]
Producer: 20110128Description: 1792-801 p. digitalISSN:- 1556-3871
- Analysis of Variance
- Animals
- CHO Cells
- Canada
- Cell Line
- Cricetinae
- Cricetulus
- Death, Sudden, Cardiac -- pathology
- Ether-A-Go-Go Potassium Channels -- genetics
- Guinea Pigs
- Humans
- KCNQ1 Potassium Channel -- genetics
- Long QT Syndrome -- genetics
- Microscopy, Confocal
- Mutation, Missense
- Myocytes, Cardiac -- physiology
- Phenotype
- Torsades de Pointes -- genetics
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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