PKA and PKC partially rescue long QT type 1 phenotype by restoring channel-PIP2 interactions. [electronic resource]
Producer: 20100706Description: 3-11 p. digitalISSN:- 1933-6969
- Animals
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Enzyme Activation
- GTP-Binding Protein alpha Subunits, Gq-G11 -- metabolism
- Genotype
- Humans
- Ion Channel Gating
- KCNQ1 Potassium Channel -- genetics
- Membrane Potentials
- Mutation
- Oocytes
- Phenotype
- Phosphatidylinositol 4,5-Diphosphate -- metabolism
- Phosphotransferases (Alcohol Group Acceptor) -- metabolism
- Protein Kinase C -- metabolism
- Protein Structure, Tertiary
- Receptors, G-Protein-Coupled -- metabolism
- Romano-Ward Syndrome -- enzymology
- Time Factors
- Xenopus
No physical items for this record
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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