CTLA4-Ig interacts with cultured synovial macrophages from rheumatoid arthritis patients and downregulates cytokine production. [electronic resource]
Producer: 20100520Description: R176 p. digitalISSN:- 1478-6362
- Abatacept
- Antirheumatic Agents -- pharmacology
- Arthritis, Rheumatoid -- drug therapy
- B7-2 Antigen -- biosynthesis
- Blotting, Western
- Cells, Cultured
- Coculture Techniques
- Cytokines -- biosynthesis
- Down-Regulation
- Enzyme-Linked Immunosorbent Assay
- Female
- Fluorescent Antibody Technique
- Humans
- Immunoconjugates -- pharmacology
- Immunohistochemistry
- Macrophage Activation -- immunology
- Macrophages -- drug effects
- Male
- Middle Aged
- Reverse Transcriptase Polymerase Chain Reaction
- Synovial Membrane -- cytology
- T-Lymphocytes -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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