C-Raf inhibits MAPK activation and transformation by B-Raf(V600E). [electronic resource]
Producer: 20100106Description: 477-86 p. digitalISSN:- 1097-4164
- Animals
- Benzenesulfonates -- pharmacology
- Blotting, Western
- Cell Line
- Cell Line, Tumor
- Cell Proliferation
- Cell Transformation, Neoplastic -- genetics
- Enzyme Activation
- Humans
- Immunoprecipitation
- MAP Kinase Signaling System
- Melanoma -- genetics
- Mice
- Mitogen-Activated Protein Kinases -- metabolism
- Mutation
- NIH 3T3 Cells
- Niacinamide -- analogs & derivatives
- Phenylurea Compounds
- Phosphorylation
- Protein Binding -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Proto-Oncogene Mas
- Proto-Oncogene Proteins B-raf -- genetics
- Proto-Oncogene Proteins c-raf -- genetics
- Pyridines -- pharmacology
- Sorafenib
- Transfection
- ras Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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