CFTR mediates apoptotic volume decrease and cell death by controlling glutathione efflux and ROS production in cultured mice proximal tubules. [electronic resource]
Producer: 20100309Description: F435-53 p. digitalISSN:- 1522-1466
- Animals
- Antibodies, Monoclonal
- Apoptosis -- drug effects
- Caspase 3 -- metabolism
- Cell Death
- Cell Line, Transformed
- Chloride Channels -- metabolism
- Cystic Fibrosis Transmembrane Conductance Regulator -- deficiency
- DNA, Complementary
- Down-Regulation
- Electric Conductivity
- Enzyme Activation -- drug effects
- Glutathione -- metabolism
- Glutathione Disulfide -- metabolism
- Humans
- Kidney Tubules, Proximal -- cytology
- Mice
- Mice, Knockout
- Reactive Oxygen Species -- metabolism
- Staurosporine -- pharmacology
- Transfection
- Tumor Necrosis Factor-alpha -- pharmacology
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Publication Type: Journal Article
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