Large T antigen promotes JC virus replication in G2-arrested cells by inducing ATM- and ATR-mediated G2 checkpoint signaling. [electronic resource]
Producer: 20100126Description: 1544-54 p. digitalISSN:- 1083-351X
- Antigens, Viral, Tumor -- genetics
- Ataxia Telangiectasia Mutated Proteins
- CDC2 Protein Kinase
- Cell Cycle Proteins -- antagonists & inhibitors
- Cell Line, Tumor
- Checkpoint Kinase 1
- Cyclin B -- genetics
- Cyclin-Dependent Kinases
- DNA-Binding Proteins -- antagonists & inhibitors
- G2 Phase
- Genome, Viral -- physiology
- Humans
- JC Virus -- physiology
- Mutation
- Nuclear Proteins
- Oligodendroglia -- metabolism
- Polyomavirus Infections -- drug therapy
- Protein Kinases -- genetics
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Protein-Tyrosine Kinases
- Signal Transduction
- Tumor Suppressor Proteins -- antagonists & inhibitors
- Tumor Virus Infections -- drug therapy
- Virus Replication -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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