A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death. [electronic resource]
Producer: 20100205Description: 366-76 p. digitalISSN:- 1471-4159
- Adaptor Proteins, Signal Transducing
- Animals
- Autophagy -- drug effects
- Carrier Proteins -- genetics
- Cell Cycle Proteins
- Cell Line, Transformed
- Cell Line, Tumor
- Dopamine -- metabolism
- Down-Regulation -- drug effects
- Eukaryotic Initiation Factors
- Green Fluorescent Proteins -- genetics
- Hydrogen Peroxide -- pharmacology
- Intracellular Signaling Peptides and Proteins -- metabolism
- Mice
- Microscopy, Confocal -- methods
- Neuroblastoma
- Neurons -- drug effects
- Oxidative Stress -- drug effects
- Phosphoproteins -- genetics
- Phylogeny
- Protein Kinases
- Protein Serine-Threonine Kinases -- genetics
- RNA, Messenger -- metabolism
- Ribosomal Protein S6 Kinases, 70-kDa -- genetics
- Signal Transduction -- drug effects
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases
- Transfection -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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