LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis. [electronic resource]
Producer: 20091110Description: 527-40 p. digitalISSN:- 1878-1551
- Anemia -- etiology
- Animals
- Apoptosis
- Apoptosis Regulatory Proteins -- physiology
- Base Sequence
- Bcl-2-Like Protein 11
- Cell Differentiation
- Cell Proliferation
- Cells, Cultured
- Colony-Forming Units Assay
- DNA-Binding Proteins -- physiology
- Embryonic Stem Cells -- metabolism
- Erythroblasts -- cytology
- Erythroid Precursor Cells -- metabolism
- GATA1 Transcription Factor -- genetics
- GTP-Binding Proteins -- physiology
- Gene Expression Profiling
- Gene Expression Regulation, Developmental
- Genes, Lethal
- Integrases -- metabolism
- Luciferases -- metabolism
- Membrane Proteins -- physiology
- Mice
- Mice, Knockout
- Mice, Transgenic
- Molecular Sequence Data
- Mutation
- Myxovirus Resistance Proteins
- Oligonucleotide Array Sequence Analysis
- Promoter Regions, Genetic
- Proto-Oncogene Proteins -- physiology
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Signal Transduction
- Transcription Factors -- physiology
- Tumor Suppressor Protein p53 -- genetics
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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