Itraconazole and rifampin alter significantly the disposition and antihistamine effect of ebastine and its metabolites in healthy participants. [electronic resource]
Producer: 20100805Description: 195-204 p. digitalISSN:- 1552-4604
- Adult
- Antifungal Agents -- pharmacology
- Butyrophenones -- metabolism
- Cross-Over Studies
- Drug Interactions
- Enzyme Inhibitors -- pharmacology
- Histamine -- adverse effects
- Histamine H1 Antagonists -- pharmacokinetics
- Humans
- Hypersensitivity, Immediate -- chemically induced
- Itraconazole -- pharmacology
- Male
- Piperidines -- metabolism
- Rifampin -- pharmacology
- Skin -- immunology
- Young Adult
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Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
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