The NRG1 gene is frequently silenced by methylation in breast cancers and is a strong candidate for the 8p tumour suppressor gene. [electronic resource]
Producer: 20091201Description: 4041-52 p. digitalISSN:- 1476-5594
- Base Sequence
- Breast Neoplasms -- genetics
- Cell Line, Tumor
- Cell Proliferation
- Chromosome Aberrations
- Chromosome Mapping
- Chromosomes, Human, Pair 8 -- chemistry
- CpG Islands -- genetics
- DNA Methylation
- Female
- Gene Expression Regulation, Neoplastic
- Gene Silencing
- Genes, Tumor Suppressor
- Genetic Predisposition to Disease -- genetics
- Humans
- Neuregulin-1 -- genetics
- Transcription Initiation Site
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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