Glucocorticoid-mediated inhibition of Lck modulates the pattern of T cell receptor-induced calcium signals by down-regulating inositol 1,4,5-trisphosphate receptors. [electronic resource]
Producer: 20091224Description: 31860-71 p. digitalISSN:- 1083-351X
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Apoptosis
- Blotting, Western
- Calcium -- metabolism
- Dexamethasone -- pharmacology
- Immunoprecipitation
- Inositol 1,4,5-Trisphosphate -- metabolism
- Inositol 1,4,5-Trisphosphate Receptors -- antagonists & inhibitors
- Lymphocyte Specific Protein Tyrosine Kinase p56(lck) -- antagonists & inhibitors
- Mice
- RNA, Messenger -- genetics
- RNA, Small Interfering -- pharmacology
- Receptors, Antigen, T-Cell -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Thymoma -- drug therapy
- Thymus Neoplasms -- drug therapy
- Transfection
- Tumor Cells, Cultured
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Publication Type: Journal Article
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