A gain-of-function TBX20 mutation causes congenital atrial septal defects, patent foramen ovale and cardiac valve defects. [electronic resource]
Producer: 20100728Description: 230-5 p. digitalISSN:- 1468-6244
- Adolescent
- Animals
- Base Sequence
- COS Cells
- Case-Control Studies
- Chlorocebus aethiops
- Chromatin Immunoprecipitation
- Circular Dichroism
- DNA -- genetics
- Female
- Foramen Ovale, Patent -- genetics
- Heart Septal Defects, Atrial -- genetics
- Heart Valves -- abnormalities
- Humans
- Male
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Pedigree
- Sequence Alignment
- Structural Homology, Protein
- T-Box Domain Proteins -- genetics
- Transcriptional Activation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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