Heat shock protein-90 inhibitors increase MHC class I-related chain A and B ligand expression on multiple myeloma cells and their ability to trigger NK cell degranulation. [electronic resource]
Producer: 20091116Description: 4385-94 p. digitalISSN:- 1550-6606
- Benzoquinones -- pharmacology
- Boronic Acids -- pharmacology
- Bortezomib
- Cell Degranulation -- drug effects
- Cell Line, Tumor
- GPI-Linked Proteins
- Gene Expression Regulation, Neoplastic -- drug effects
- HSP90 Heat-Shock Proteins -- antagonists & inhibitors
- Histocompatibility Antigens Class I -- biosynthesis
- Humans
- Intercellular Signaling Peptides and Proteins -- biosynthesis
- Killer Cells, Natural -- immunology
- Lactams, Macrocyclic -- pharmacology
- Ligands
- Multiple Myeloma -- immunology
- Protein Folding -- drug effects
- Pyrazines -- pharmacology
- Up-Regulation -- drug effects
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.