mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging. [electronic resource]
Producer: 20091104Description: 279-89 p. digitalISSN:- 1875-9777
- Animals
- Antigens, CD34 -- metabolism
- Cell Proliferation -- drug effects
- Cell Separation
- Cellular Senescence -- drug effects
- Doxycycline -- pharmacology
- Epidermal Cells
- Epithelial Cells -- cytology
- Hair Follicle -- cytology
- Keratinocytes -- cytology
- Mice
- Protein Kinases -- metabolism
- Regeneration -- drug effects
- Signal Transduction -- drug effects
- Sirolimus -- pharmacology
- Stem Cells -- cytology
- TOR Serine-Threonine Kinases
- Wnt Proteins -- metabolism
- beta Catenin -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Intramural
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