Role of the macrophage inflammatory protein-1alpha/CC chemokine receptor 5 signaling pathway in the neuroinflammatory response and cognitive deficits induced by beta-amyloid peptide. [electronic resource]
Producer: 20091209Description: 1586-97 p. digitalISSN:- 1525-2191
- Amyloid beta-Peptides -- toxicity
- Animals
- Cell Movement -- drug effects
- Chemokine CCL3 -- metabolism
- Cognition Disorders -- metabolism
- Cyclooxygenase 2 -- metabolism
- Gene Deletion
- Hippocampus -- drug effects
- Humans
- Inflammation -- metabolism
- Male
- Memory -- drug effects
- Mice
- Mice, Inbred C57BL
- Nervous System -- drug effects
- Neuroglia -- drug effects
- Nitric Oxide Synthase Type II -- metabolism
- Peptide Fragments -- toxicity
- Receptors, CCR5 -- metabolism
- Signal Transduction -- drug effects
- Synapses -- drug effects
- Transcription Factors -- metabolism
- Up-Regulation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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