MEKK1 binds HECT E3 ligase Itch by its amino-terminal RING motif to regulate Th2 cytokine gene expression. [electronic resource]
Producer: 20090923Description: 3831-8 p. digitalISSN:- 1550-6606
- Animals
- Binding Sites
- Cytokines -- genetics
- Gene Expression Regulation
- MAP Kinase Kinase 4 -- metabolism
- MAP Kinase Kinase Kinase 1 -- metabolism
- Mice
- Mice, Knockout
- Phosphorylation
- Protein Binding
- RING Finger Domains
- Receptors, Antigen, T-Cell -- metabolism
- Th2 Cells
- Ubiquitin-Protein Ligases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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