A single amino acid change (Y318F) in the L-arabitol dehydrogenase (LadA) from Aspergillus niger results in a significant increase in affinity for D-sorbitol. [electronic resource]
Producer: 20090914Description: 166 p. digitalISSN:- 1471-2180
- Amino Acid Substitution
- Aspergillus niger -- enzymology
- D-Xylulose Reductase -- genetics
- DNA, Fungal -- genetics
- Genes, Fungal
- L-Iditol 2-Dehydrogenase -- genetics
- Models, Molecular
- Mutagenesis, Site-Directed
- Mutation
- Phylogeny
- Sequence Analysis, DNA
- Sorbitol -- metabolism
- Substrate Specificity
- Sugar Alcohol Dehydrogenases -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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