Long-term proton pump induced hypergastrinaemia does induce lineage-specific restitution but not clonal expansion in benign Barrett's oesophagus in vivo. [electronic resource]
Producer: 20100323Description: 156-63 p. digitalISSN:- 1468-3288
- Adult
- Aged
- Barrett Esophagus -- drug therapy
- Cell Movement -- drug effects
- Cell Proliferation -- drug effects
- Dose-Response Relationship, Drug
- Enzyme-Linked Immunosorbent Assay -- methods
- Esophageal Neoplasms -- drug therapy
- Esophagus -- metabolism
- Female
- Gastric Mucosa -- metabolism
- Gastrins -- biosynthesis
- Gene Expression
- Humans
- Male
- Middle Aged
- Precancerous Conditions -- drug therapy
- Proton Pump Inhibitors -- adverse effects
- RNA, Messenger -- genetics
- Receptor, Cholecystokinin B -- biosynthesis
- Reverse Transcriptase Polymerase Chain Reaction -- methods
- Tumor Cells, Cultured
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Publication Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
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